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Macdonald IA

It stimulates lipolysis (breakdown of stored fats) and inhibits lipogenesis (formation of new fat), primarily via activation of -adrenergic and AMP-activated protein kinase (AMPK) pathways

In some instances, sterilization of an auris formulation by filtration through membranes (e.g., 0.2 M membranes) is not possible if the formulation comprises thixotropic polymers that gel during the process of filtration